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Although recent genome-wide association studies have identified several loci associated with pubertal timing and age at menarche, the genetic causes of CPP are still largely unknown.
Although we have no clear explanation, the difference between our and previous results could stem from differences in timing and age characteristics of the studied samples.
We evaluate the evidence that fishing is causing evolutionary changes to traits including body size, migration timing and age of maturation, and we discuss the implications for fisheries and conservation.
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Using detailed demographic information for the GVRD, we have developed a compartmental mathematical model to estimate the transmission of pH1N1 in this population and to examine the impact of timing and age-specific coverage of different vaccination strategies for reducing the disease burden of pH1N1.
The timing and age-specificity of deleterious alleles are properties that are central to the evolutionary theories of ageing, mutation accumulation and antagonistic pleiotropy [ 17, 18] and are essential for an understanding of the evolution of survival patterns, e.g. late-life mortality plateaus [ 19].
Hatchery fish continued to have significantly lower fitness after accounting for weight, run-timing, and age (three variables that also had an effect on fitness).
A 43-year old illustrates how timing and her age are the primary reasons for seeking abortion " Because I'm too old to have a child.
For instance, we found that the age (timing) and rate (magnitude) of loss in both balance and gait speed were both similar for men and women, with balance deteriorating at an earlier age than gait speed (60 70 years vs 70+ years) in both sexes.
They play important roles in many biological processes, including developmental timing, cancer, and aging.
Finally, the relation between functional outcome and type of fracture, timing of intervention and age was assessed.
We traced the relationship between replication timing and the evolutionary age of duplicated genes.
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