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The transmission model may easily be estimated with likelihood-based approaches from complete data that consist of the times of colonization and decolonization for each child.
This lack of knowledge may stem from the difficulty to analyze field data on colonization, which generally consist of samples irregularly spaced in time, and lack information about the times of colonization and decolonization.
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The primary parametric expectation that distinguishes marine vicariance (H 1 ) from colonization (H 2 ) is the relatively small effective population size of the colonized population 2) at the putative time of colonization (τ C ). Secondarily, the possibility of gene flow subsequent to the vicariance event τ V further distinguishes H 1 and H 2, although this assumption can potentially be relaxed.
In a prospective study of hospital patients showed that at the time of colonization, IgG levels were higher in asymptomatic C. difficile colonized patients compared to patients who subsequently developed diarrhea [ 18].
At the time of colonization, the dodo did have at least one close relative — a slenderer bird on the island of Rodrigues, three hundred and fifty miles east of Mauritius.
At the time of colonization, the Spanish named the major Chumash groups the Obispeño, Purismeño, Ynezeño, Barbareño, and Ventureño (for the Franciscan missions San Luis Obispo de Tolosa, La Purísima Concepción, Santa Ynez, Santa Barbara, and San Buenaventura, respectively), the inland Emigdiano and Cuyama, and the Isleño.
To estimate a person's time of death, forensic investigators must look at the insects on the body and determine the time of colonization (Kulshrestha and Satpathy 2001).
On the local level, the basic administrative units were the vici, replacing the Helvetic pagi, or tribes, which were dissolved at the time of colonization.
Another theory suggests that during the time of colonization, European countries mostly focused on expanding into regions with temperate climates, therefore limiting contact with people in tropical areas where most of the high biological and linguistic diversity still occurs.
We used blood samples and cytochrome b (cyt b) sequences available from Genbank (Table S1) from all subspecies in order to estimate phylogenetic relationships and time of colonization of F. teydea and F. coelebs in Macaronesia.
However, even for a normally recombining population, factors such as foundation by a limited number of individuals, random genetic drift in small populations, or immigration of individuals from populations with different allele frequencies can artificially create nonrandom associations between unlinked markers (i.e., linkage disequilibrium) at the time of colonization of a new territory.
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