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However, in case of testing timeline expression profiles for periodicity independence could not be assumes for a number of reasons.
Given this maturational timeline, expression of Arc in 1 and 7 day old cells (Fig. 5d,e and 7), must precede glutamatergic synapse formation onto these cells.
However, in the case of testing timeline expression profiles for periodicity, independence cannot be assumed.
The timeline expression profiles reported in Drosophila [ 43] are similar for the genes forming circadian molecular clock.
Furthermore, considered in the broader context of gene interaction networks, timeline expression can help the reverse-engineering of biological pathways, identify alternative transcripts and potential drug targets.
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In neurodegenerative lesions, the timeline of CSPG expression is not well understood, as all histopathology in humans occurs post-mortem.
(A ) Representative Western blots showing the developmental timeline for hevin expression in mouse cortex and hippocampus (tubulin was used as a loading control).
We also used SV40-transformed and non-SV40-transformed cell lines to characterize the levels and timeline of miRNA expression following infection with the virus.
The utility of understanding the timeline of gene expression throughout the entire transcriptome is not an academic exercise limited to understanding circadian behavior.
On the basis of its expression timeline, which parallels that of the cilia-related proteins Spag6 (sperm-associated antigen 6) and Hydin, WDR16 was proposed to play a role in cilia-related signal transduction processes.
A 72 h timeline of hepcidin expression post-exercise was assessed, which showed that the hepcidin level significantly elevated at 3, 6 and 24 h post-exercise, and then declined from there, reaching baseline at 72 h post-exercise [ 37, 38].
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