Dextran flux was assessed to determine the experimental timeframe of 6 hours, in agreement with previous work with large molecule transport [ 26]. 6 hours prior to the experiment, cell medium was changed to 2% FBS. 10 μg/mL adiponectin and dextran were applied above the monolayer (luminal side) to the top well.
Furthermore, MRI-based treatment in the timeframe of 0 6 hours also shows similar or superior safety and efficacy to CT-based treatment within 3 hours, when compared directly [ 89] or with data from a meta-analysis [ 90].
The timeframe of phantom sensations (reportedly in hours or days) [ 93, 94] does not appear to match those of sprouting (in weeks or months) or disinhibition (in seconds and minutes), suggesting that other mechanisms of remapping might be involved.
In fact, previous studies showed that AZA (2 8 µM) induction of apoptosis in the human AML cell line HL-60 was preferential to G1-phase cells and occurred in a short timeframe (4 8 hours), implicating an RNA mechanism [30], [31].
The best performance of sNGAL in predicting DGF was seen in the small group of cases with a timeframe of six hours or less from reperfusion to blood sampling.
In our simulations (Fig. 3), we assume that the system reaches a steady state within the experimental timeframe of 2 hours.
Importantly, developments in computing, automation and high-flux synchrotron sources have propelled the rapidity of 'conventional' RNA crystal structure determinations to timeframes of hours once a suitable set of phases is obtained.
Integrative sampling enables the collection of analyte mass from environmental liquids over extended timeframes from hours to months.
That's important because three hours from the onset of stroke symptoms is the timeframe in which a clot-busting medication called tissue plasminogen activator (tPA) is likely to help.
It is important to note that these dramatic changes occurred in a relatively short timeframe, only six hours after immunostimulation.
I don't have any particular timeframe in mind.
