Yamamoto, T. et al. Time-dependent dysregulation of autophagy: Implications in aging and mitochondrial homeostasis in the kidney proximal tubule.
Our study shows that microglia respond to environmental challenges in a sex- and time-dependent manner from prenatal stages, with major implications for our understanding of microglial contributions to health and disease.
The design and mathematical implications of such a time-dependent dynamic impact assessment is considered by Motzek et al. in [11] utilizing so-called activator dynamic Bayesian networks [49].
Analytical techniques and methodologies facilitate key decisions during the discovery of atropisomeric drug candidates by characterizing time-dependent physicochemical properties that can have significant biological implications and relevance to pharmaceutical development plans.
The origin of the differential wear between grains is considered and the implications of the experimental observations on the time-dependent transition to severe wear in aluminas are discussed.
The time-dependent risk profile of prognostic factors may have important clinical implications in regard to follow-up and patients' individual risk situation.
The results may have implications not only for understanding of the viscoelastic time-dependent mechanical behavior of the ITA and SSV but also for tissue engineering applications to make scaffolds according to the real time-dependent viscoelastic mechanical properties of these arteries and veins.
Shirzaei, M., Bürgmann, R. & Taira, T. A. Implications of recent asperity failures and aseismic creep for time-dependent earthquake hazard on the Hayward fault.
Shirzaei, M., T. Taira, and R. Bürgmann (2013), Implications of recent asperity failures and aseismic creep for time-dependent earthquake hazard on the Hayward fault, Earth and Planetary Science Letters, 371-372, doi 10.1016/j.epsl.2013.1004.1024.
Time-dependent expression of this mRNA consequently resembles the pattern of DHX58, again suggesting a functional implication of the encoded protein in response to infection.
These observations illustrate the power of imaging systems for deciphering breast cancer biology, where the data have implications for interpreting whole tumour microarray/proteomic profiles and clearly confirm that time-dependent study of metastasis at a cellular level is essential.
