The last noteworthy advantage of our framework is that the training data for the semi-supervised formulation are the positive and negative controls, which are easily recognizable and obtained without time-consuming annotation, sidestepping the limitation of training sample size of many metric learning algorithms.
These manual tests can be tedious and time-consuming and have many limitations such as the inability to document the test results and the difficulty in replicating field conditions.
Current diagnostic screening strategies based on karyotyping or fluorescent in situ hybridization (FISH) for detection of chromosomal abnormalities in chronic lymphocytic leukemia (CLL) are laborious, time-consuming, costly, and have limitations in resolution.
These methods are usually time-consuming and have potential limitations with respect to the accurate identification of rare pathogens and of cryptic species of Candida [ 6].
The traditional drillability measurement using micro-drilling test has the limitations of time-consuming data acquisition and low utilization efficiency of core samples.
Although multiple samples provide information on the overall exposure in infants, this approach is costly, time-consuming, and subject to ethical limitations and might not capture some key events in the lifetime toxicokinetic profiles of POPs.
Another limitation is the time-consuming and cost-intensive method of electrode evaluation.
The results of the current study revealed that ELT teachers believed that implementing self-assessment and peer-assessment are challenging due to the practicality issues such as being time consuming and limitation in resources, thus supporting the results of the previous studies in this regard (eg Bullock 2011).
However, the currently available materials based mainly on polymethylmethacrylate (PMMA) still encounter certain limitations, such as time-consuming polymerization, thermal and chemical necrosis and troublesome revision procedure.
However, these two technologies have several limitations, including the time-consuming and labor-intensive experimental design, and the risk of off-targeting mutations (Gaj et al., 2013).
