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To calculate the P-value for the test that gene i is differentially expressed, RP i is compared with its permutation distribution under the null hypothesis that R ij for i = 1,…, n are exchangeable within each microarray j. 1 However, to accu-rately approximate the distribution, a very large number of permutations is required, which becomes very time-consuming computationally.
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This improves the misses cost but requires to repeat the procedure for every transaction and sensitive itemset; it is a time consuming, computationally expensive and sometimes infeasible procedure for Big Data and a parallel environment.
However, such time consuming, computationally intensive tasks rely on knowledge of substitution model theories and related expertise to run through all possible combinations of several separate programs.
Clearly, this is a time-consuming and computationally intensive task.
Complex system engineering design optimization based on simulation is a very time-consuming, even computationally prohibitive process.
Because the multi-layer optimization problem is typically time-consuming and computationally expensive, the adaptive surrogate model is constructed using data drawn from the multi-layer optimization model and provides a fast approximation of the objective at new design points.
However, this space reduction is very time-consuming and computationally intensive considering a large amount of documents in our collection.
From this experience, we realized that we needed to find the time-consuming, less computationally intensive parts of the source code and remove them.
A clear disadvantage of these methods is that the estimation of the parameters may not be straightforward, being time-consuming and computationally demanding.
In practice, it is hard to solve the ARE, and there is no general method unless the system matrices are special and there are some methods and algorithms to solve (1.4); however, the solution can be time-consuming and computationally difficult, particularly as the dimensions of the system matrices increase.
3D CFD modelling is therefore time-consuming and computationally demanding.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com