In addition to brain MRI, lumbar puncture, brain MRA and MRA of carotid/vertebral arteries are also recommended to rule out subarachnoid hemorrhage and arterial dissection on first occurrence of exercise headache, assuming time to peak severity of headache is short, i.e. in minutes.
The optimal time to measure severity of illness is just prior to the onset of bacteremia, but this time period is difficult to identify.
Time to meet severity criteria for discharge (PRAM <4) and length of active treatment are two additional measures of interest that are less influenced by factors other than severity.
BTP has historically been managed with short-acting opioids; however, these medications have a pharmacokinetic profile that does not correlate with the sudden onset and short time to maximum severity of BTP.
Reaction severity is a comprehensive parameter which combines temperature and time to describe the severity of a process.
Secondary outcomes are time to, duration and severity of relapse/recurrence, quality of life, personality, several process variables, and incremental cost-effectiveness ratio.
Thus, we propose some minor changes in the thunderclap diagnostic criteria modified by Dodick et al. [2]: (a) time to reach peak severity up to 60 s; (b) headache duration of 5 min or longer, since the explosive type of headache occurring during sexual activity is considered to be a thunderclap headache [46] and may be of short duration.
23 Exacerbations 24: frequency of exacerbations, time to first exacerbation, severity and duration of exacerbations.
The administration of corticosteroid premedication has been shown to reduce the time to onset and severity of fluid retention and is given to all patients.
Estimated time to complete the severity scoring form was 30 seconds, to enter a new patient on the database was 90 seconds and to calculate risk of death and check data integrity was 90 seconds.
Conventional diary cards and the case report forms used in vaccine clinical trials typically describe adverse reactions in terms of quantitative variables (time to onset, duration, severity and outcome).
