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Significant independent prognostic factors for time to mortality were diabetes, coronary artery bypass graft surgery, a history of malignancy, narcotics use, smoking, volume depletion and atrial fibrillation [19].
The combination of AZM with CFZ increases bacterial clearance from spleen and blood and delays the time to mortality in a murine sepsis model by P. aeruginosa.
Mice were monitored twice daily and the mean time to mortality between the groups was determined.
During our experiments, the larvae entered chill coma early in the cooling process, so it is not possible to pinpoint time to mortality from our recordings.
Among parametric survival models, the loglogistic model provided the best fit (lowest AIC) to the HPAI time to mortality data (Table S1 and Figure S2).
We further speculate that the Cz-mediated reduction in extracellular growth in the lung allowed the mouse immune system to delay the eventual dissemination of Cn, increasing the time to mortality.
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The longer time-to-mortality in our desiccation treatment is likely to be due to the plant fragments and animals remaining enclosed in damp nets which retained water for a number of days after initial submersion whereas the plants/animals were not enclosed in the aforementioned studies.
Multivariate analysis of the time to ICU mortality was calculated using Cox regression model and for hospital, 6-months and 1-year mortality using logistic regression analysis.
In the trauma cohort, 25-OHD levels were also not significantly associated with time to hospital mortality - hazard ratio 0.59 (95% CI 0.3 to 1.20), (P = 0.14) (Table 3).
Cox proportional hazards models were used to examine the time to CHD mortality.
However, time to 50% mortality was found significantly the lowest in SBM45 group.
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