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Helped by the academic Simon Davies, of the London School of Economics, the organisation examined a host of pubs' claims to have been part of a moment of history, and has made an initial list of 14 that could now be commemorated with a Pubs in Time plaque.
Given time, plaque can mineralize along the gingiva, forming tartar.
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After two rounds of limited dilutions, three different individual recombinant clones for each protein were selected to run 2 or 3 times plaque assays to remove parent virus contamination.
For the first time, ruptured plaque or plaque at high risk of rupture can be identified noninvasively which as the authors postulate, carries the potential to alter management of stable and unstable coronary artery disease.
The relative proportions of these two markers varied considerably between plaques, consistent with differences in time between plaque rupture and surgical removal of the plaque at endarterectomy.
Plaque development as a function of increasing concentration of the antibody has shown that each mutant of a matched pair yielded the same number of plaques, although the high fitness mutant required less time for plaque formation, and attained a larger plaque size at any given time-point.
Over the same time period, plaque volume increased significantly immediately after the plaque's appearance (Fig. 6c, p < 0.05, Wilcoxon signed-rank test against theoretical value 0 μm).
In conclusion, newly appearing amyloid plaques are initially small in size but grow over time until plaque growth can not be detected anymore in aged mice.
Our results show, for the first time, that plaque age, as judge by relative incorporation of 14C, can improve our understanding of carotid plaque stability and therefore risk for clinical complications.
It later became a takeaway pizza house (during which time the plaque was put up) and is now Le Pain Quotidien bakery.
The difference has partly to do with memories of movies -- all kinds -- that build up on the critic's mind, automatically, over a period of time, like plaque on teeth.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com