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What are the mechanisms that initiate the ordered progression of the cell cycle?
As per protocol, dexamethasone (0.5 mg daily) was added at the time of progression in order to evaluate whether steroids could reverse the possible effects of excess ACTH and upstream steroids.
As mentioned in Methods, in this work we reduced the concentration from 7.5 mM to 1 mM in order to extend the time of progression of symptoms.
Surgical treatment suffices for the majority of NETs, but malignant, recurrent, and metastatic tumors need further treatment in order to gain a lengthening of time to progression [ 65].
For instance, the same animal can be imaged multiple times in order to monitor visually, often in real time, the progression or regression of infection or disease.
In order to identify a miRNA signature for chemotherapy resistance, we correlated miRNA expression levels with the time to progression (TTP) of disease after CF therapy.
Median time to progression is 12.4 months.
Time to progression (TTP) was defined as the time from the date of registration until the date of disease progression.
The median time to progression was 3.5 months.
Median time to progression was 5.1 months (95% CI: 3.3 6.7).
The primary endpoint was time to progression (TTP).
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