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However, as the monomer content increases the monomer conversion and polymerization rate at stage I will rapidly decrease while the ending time of stage I rapidly increase.
Although systematic medical checks and the development of surgical treatments have contributed to the early detection and improved prognosis of GC, the median survival time of stage IV gastric cancer remains only 10 12 months [2].
Moreover, for St and MMA, the model predicts that as the ultrasonic intensity increases the monomer conversion and polymerization rate at stage I will rapidly increase while the ending time of stage I rapidly decrease.
The median survival time of stage IV patients with a high number of LC3A‐positive SLS was 3.55 months versus 13.6 months for those with a low number.
A total of 855 patients (56.4% male) with primary cutaneous melanoma were included in the survival analysis at the time of stage IV diagnosis.
It has been reported that the median survival time of stage IV melanoma patients is about 6 7.5 months, the 5-year survival rate being approximately 6% (Bajetta et al, 2002).
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Proper determination of the extent of disease on imaging studies at the time of staging is one of the most important steps in optimal patient management.
At the time of staging, all patients had an Eastern Cooperative Oncology Group (ECOG) performance status of ≤2.
CA 19-9 kinetics were significantly correlated with TTP and OS only at time of staging (day 56).
At the time of staging (day 56), absolute levels of each analysed marker again showed a significant correlation with objective response.
All consenting patients are assessed for the presence of CK-19mRNA CTCs as part of their laboratory evaluation at the time of staging of their recurrent or newly diagnosed metastatic disease and before starting any systemic treatment.
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