Sentence examples for time of replication from inspiring English sources

In higher eukaryotes, it has been observed that the time of replication and transcriptional activity are often correlated; genes which are late replicating are not expressed while transcriptionally active regions are early replicating [47].

Because the parameters t0 and a are unknown, we cannot extract the absolute time of replication.

For comparison with time of replication and conserved elements, similar analyses were performed except that the number of overlapping bp between SARs and the target data set was assessed.

Thus, the finding of fewer SARs in heterochromatic regions, defined by time of replication and association with nuclear periphery, is likely due to the compact nature of the chromatin that will accommodate larger chromatin loops generated by the more infrequent scaffold attachment sites.

Higher numbers indicate an earlier average time of replication.

However, the activation time of replication origins in S phase is different.

Plasmids p5-6C and p5-6m7C were transformed separately into S. cerevisiae and their times of replication were determined in parallel cultures using a modified version of the Meselson-Stahl density shift experiment with synchronized cultures (McCarroll and Fangman 1988).

Moreover, in human, GMNN (geminin), which negatively regulates DNA replication 'licensing' (the one time initiation of replication in a single cell cycle) by preventing the formation of the pre-replicative complex on origins of replication through the physical association with the 'licensing' factor Cdt1 [ 41, 42], was cleaved by CASP3 during apoptosis [ 43].

In short, Darwin's theory of natural selection states that complex organisms evolved through time because of replication, mutation, and replication of mutations.

In addition, levels of gene expression have been found to correlate with time of chromatin replication during the cell cycle, i.e. the early replication of actively expressed regions of the genome [ 15].

However, it is difficult to configure (commit_interval) since the hardware may be not same in different production environments and the processing time of log replication in Followers should be considered.