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All animals were symptomless at the time of euthanasia.
The SPG was carefully dissected out, close to the time of euthanasia, by initially making an incision over the zygomatic bone.
Here we report that 22 out of 23 of these animals successfully controlled their viremia until their time of euthanasia at 200 weeks postchallenge.
Here, we characterize swarm SHIV AD8) stocks, prepared from three infected rhesus macaques with documented immunodeficiency at the time of euthanasia, for their capacity to establish durable infections in macaques following inoculation by the intravenous (i.v). or intrarectal (i.r). route.
Blood was periodically collected throughout the infection and at the time of euthanasia.
Fig. 5 shows the change in body weight of all mice at the time of euthanasia.
At the time of euthanasia, the visceral organs were removed by dissection, fixed in 4% formaldehyde, and paraffin-embedded.
The estimated time of natural death for these mice was ≤1 or 2 days from the time of euthanasia.
Full necropsies were performed on tumor-bearing animals after 60 days or at the time of euthanasia.
We administered to R6/2 mice the PDE10A inhibitor, TP-10, beginning at 4 weeks of age, before the development of neurological impairment, until the time of euthanasia.
Skeletal muscle and BAT samples were collected at the time of euthanasia and immediately stored in RNAlater (Ambion, USA) at −20°C.
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