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All patients enrolled into the study had progressive disease at the time of enrolment.
At the time of enrolment, children were examined clinically.
None had started treatment at the time of enrolment.
All the study participants were living in Belgium at the time of enrolment.
All subjects were therapy-naïve at the time of enrolment and during follow-up.
†Status at time of enrolment.
Maternal anthropometrics were assessed at time of enrolment.
Informed consent was obtained at the time of enrolment.
Medications at time of enrolment are shown in Table 1.
At the time of enrolment, each patient was assigned a unique study identification number.
Parents can be asked to consent at the time of enrolment.
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