Event-free survival (EFS) was defined as time from study entry until removal from study because of failure to achieve complete remission, first relapse, or death from any cause.
Disease-free survival (DFS) was defined as time from study entry to local or distant disease relapse, OS as time from study entry to death of any cause.
Time from study entry to first major limb amputation and time from study entry to death were evaluated separately as censored event times by Kaplan-Meier curves.
Larger ROI volume was positively associated with increased time from study entry (R = 0.28, P = 0.0443).
Time to tumour progression was defined as the time from study inclusion to documented progressive disease.
Overall survival was defined as the time from study enrolment to death.
OS was defined as time from study entry to death or last follow-up.
Overall survival was defined as the time from study entry to death of any cause.
Overall survival was defined as the time from study entry to death due to any cause.
Survival was defined as the time from study entry to death from any cause.
Survival time was defined as the time from study registration to death due to any cause.
