The short time frame of the test and the limited number of animals needed lend further support to the assay.
It is assumed that the equilibrium steady state is not reached within the time frame of acute toxicity testing for substances with a high Kow.
As TBI is associated with acute weight loss, and this weight loss occurs during the time frame of motor skill testing, we questioned if the improved motor skill performance we observed could be due to a reduction in post-trauma weight loss.
In our opinion, if the haematorit values of consecutive postoperative 5 days have the tendency to decrease continuously, and the lowest haematocrit value may not appear during this period, prolonging the time frame of blood routine test is needed until the lowest haematocrit value emerges for the purpose of accurate assessment.
Furthermore, the ATPS utilized could be optimized to achieve rapid phase separation within the time frame of typical LFA diagnostic tests, so that the complete detection assay, including the concentration step, could be completed within an hour.
To further test the time frame of Chk1 dependence, we added MK-8776 at different times after gemcitabine.
Third, the short time frame of genealogical interest mandates an approach carefully testing the coalescence confidence intervals of any given potential founding lineage, rather than using simple coalescence analysis.
There was no effect on glycaemia measured by HbA1c, but the power and time frame of our trial were not designed to test for this effect.
One-dimensional NMR data indicated that DCS was stable and consisted of a single chemical species across all pHs tested over the time frame of the experiment (data not shown).
The auxin effect on vacuoles was in the time frame of fast transcriptional responses and, subsequently, we tested whether the TRANSPORT INHIBITOR RESISTANT1 (TIR1)/AUXIN F-BOX PROTEINS (AFB) auxin receptors (Leyser, 2006; Mockaitis and Estelle, 2008) are required for the auxin effect on vacuoles.
