From a methodological perspective, an ideal COI study would clearly describe the perspective of analysis and, hence, the cost items (direct or indirect), cost collection procedure, discounting, quality of data, time frame of analysis, related comorbidities, and robust sensitivity analysis for all the assumptions.
With the exception of the time frame of Backman and colleagues, who measured health-related quality of life at 6, 12, 24, and 36 months [ 24], time frames for outcome measurement were short.
The specific objectives of this study were to: 1) develop a detailed quality assessment tool that could quantify the quality of expert answers provided within the ECORN-CF project, 2) evaluate the intra- and inter-rater agreement of the quality assessment tool, and 3) explore changes in quality of expert answers over the time frame of the ECORN-CF project.
The time frame of search was extended in order to identify better-quality estimates for Italy, Spain, Moldova and Portugal.
A within trial analysis was conducted comparing the costs and quality adjusted life years (QALYs) measured within the time frame of the trial.
Individual assessment of health levels, well-being, joint pain and the quality of life is quite unsteady, even within a time frame of about two months.
The time frame of the French exhibition is important.
WorldPost: What is the time frame of your thinking?
The time frame of this study will be 18 months.
