The molecular mechanisms involved allow time for accumulated damage to occur and include free radicals, advance glycation end-products, apoptosis and senescence.
For example, to avoid degradation of the tissue architecture, LV-transduced human colon tissues had to be analyzed after no more than 24 hours of explant culture, and the time course for accumulating a detectable level transgene product may require a longer time interval for epithelial cells.
To stock the United States team with golfers whose current form was the best, Azinger reduced the time frame for accumulating points to one year from two.
The early timing hypothesis does not reject the premium that late-entry children enjoy initially, but it suggests that the gains from late school entry are transitional and will be offset by time losses for accumulating labor market experience and experiencing alternative life events.
We first give a brief explanation of the constant time filtering process for accumulating the contributions to the expected energy and then show how the filter is employed in our two-pass algorithm.
It has often been speculated that apomicts cannot be sustained in nature for a long period of time due to their propensity for accumulating mutations in the absence of sexual reproduction.
Different colors correspond to different assumptions about the cost for accumulating evidence over time.
'no cost' corresponds to the case shown in panel A. 'cost 0.1' and 'cost 0.2' assume a cost per second for accumulating evidence over time.
When the arbiter finally sent off John Heitinga in extra time, that was merely for accumulated offenses.
