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In this study, cellular metabolic responses to imatinib treatment, including mitochondrial activity and glucose utilisation, energy production and membrane turnover were investigated in a time-dependent matter following the cells on their path in becoming resistant to imatinib (for a summary of these effects, please refer to Figure 5).
Trip time dependent on tides.
(a) concentration dependent (b) time dependent.
The new solver is essentially based on a Monte Carlo scheme with time dependent cross sections implying the on-the-fly resolution of a reduced model for each MC particle describing the time evolution of the matter along their flight path.
Caries increment is time dependent.
This effect was time dependent.
NETs killed B. pseudomallei effectively, and neutrophils stimulated with B. pseudomallei showed increased elastase and DNA release in a time- and dose-dependent matter.
After prolonged hypoperfusion, white matter damage progressed in a time-dependent manner in AM+/− group compared with the wild-type group.
These results suggest that AM inactivation promotes the decrease of OLGs in a time-dependent manner after prolonged cerebral hypoperfusion, which significantly progressed white matter injury.
Indeed, the need for MIC coverage for 100% of the dosing interval with time-dependent antimicrobials is a matter of debate.
Here we report that single TBI using CHIMERA induces injury dose- and time-dependent changes in behavioral and neurological deficits, axonal damage, white matter tract microgliosis and astrogliosis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com