This interpretation gains strength from a signal elsewhere in the phylogeny: haplogroup M1 in Sardinia also presents a rather star-like clade [ 23] dating to 5.2 ka, based on ρ and the time-dependent clock.
The global state for simulation is defined to include at least a simulation clock to enable time dependent computation.
Trip time dependent on tides.
We propose that for mammals with polyphasic/nonwake consolidating sleep, the local BMAL1-dependent clock directs appropriately timed declines and increases in histamine biosynthesis to produce an appropriate balance of wake and sleep within the overall daily cycle of rest and activity specified by the SCN.
These results are consistent with the caveat that the time-dependent process uses a tree-dependent clock rather than the more biological situation of a duplication-event specific process.
Here we report that the time-dependent expression of core clock components in human neutrophils characteristically differs from that in mononuclear cells.
In conclusion, human mitochondrial DNA clock is time-dependent mainly because of the time-dependence of purifying selection.
We propose that the local BMAL1-dependent clock mechanism suppresses daytime histaminergic tone and thereby facilitates appropriately timed intervals of sleep and wake synchronized to the animal's overall circadian behavior.
Is there evidence of temperature-dependent clock gene expression prior to the entrainment of the clock by temperature?
The significant Group * Treatment interaction (Table 1) indicates that the Per1 and Per2 responses to light differ according to the time of the night, reinforcing the idea that the light pulse induces a time-dependent effect on these two clock genes (Figure 1&2).
The feature of the LFP that most effectively can determine the pace of a local clock is its time-dependent phase.
