Physicochemical filtration, time-dependent blocking due to filling of favorable attachment sites and colloid-facilitated transport were identified as the major processes for AgNP mobility.
Time-dependent blocking and ripening retention were described using a Langmuir-type equation with a rate coefficient that respectively decreased and increased linearly with the retained concentration.
The sensitivity information is stored in the n y n t × n p dimensional sensitivity matrix S. S is a block matrix that consists of time dependent blocks s(t i ) of size n y × n p [ 34]: (7) The entries of s(t i ) are called sensitivity coefficients.
Results of a time dependent attachment (blocking) and detachment model were not consistent with this behavior because the simulations predicted much less retention near the column inlet and a decreasing number of favorable attachment sites (mass of deposited colloids) with increasing input concentration in a given system (colloid and sand).
Networks are observed at specific time points, termed 'snapshots', and the goal is to infer or estimate the time-dependent block model given the snapshots.
We found that when the channels were fully open at pH 5.0 and 1 μM THexA applied (i.e., the IC50 value), then the currents exhibited a slow time-dependent block to ∼50% of the original current (n=5, Figure 6A) and a similar slow recovery from inhibition.
In the presence of the P450s, the inhibitory effects of APAP on purified TrxR were concentration- and time-dependent, and blocked by α-naphthoflavone and ketoconazole, inhibitors of CYP1A2 and CYP3A4, respectively.
The models included outcome data from two time periods for each participant (pre-program and post-program) along with baseline and time dependent covariates identified from the block models (sex, marital status, aerobic exercise score, cognitive symptom management, self-rated health).
Additionally membrane blocking efficiency can be studied by time dependent fluorescence measurements.
The time dependent variations in VCDL, the most sensitive blocks of DLL, are analyzed.
It also can not include variations in the response over time - e.g. when combining observations separated by multiple years, time dependent quantities, such as the amount of contamination on the ACIS optical-blocking filters, are not handled correctly.
