Manual searching of parcels deemed suspicious on external visual inspection may be time consuming, subject to significant error, and risks damage to the handled parcels.
Water displacement volumetry is considered as the gold standard despite some important limitations since it is rather time consuming, subject to different error sources [ 7] and cannot be applied to patients with skin ulcers, a common complication of advanced CVI [ 4].
"The last reorganisation in Wales started in 1991 and finished in 1996 and was hugely time consuming, costly and subject to significant political controversy.
Animal experiments to test the cytotoxicity of dental materials are time consuming, expensive, and subject to extensive public discussions.
Available alternative means of describing species diversity, either from molecular or morphological data have major drawbacks in that they are time consuming, expensive, or subject to their own biases and inaccuracies.
Although 24 hour urine collection for total protein is still used as the gold standard for comparison of tests for proteinuria, this test itself has many limitations, as discussed in the introduction namely, that it is time consuming, inconvenient, and subject to errors such as incomplete collection.
Although time consuming (>20 h per subject), it ensures that the cross-frequency coupling results were due to the precise timing of the relationship between high frequency power and lower frequency phase and were not due to changes in overall power or phase distribution.
Despite the development of specific protocols and restraint devices, training in preparation of imaging of awake rodents and primates [ 1, 2] is time consuming; often only, few subjects prove to be suitable candidates for awake imaging [ 3], possibly biasing the population selection.
However, these cohort studies are time consuming, logistically difficult, expensive, and subject to biases related to enrollment, behavior change, preventive measures, interventions, loss to follow-up and other study effects.
Methods currently available are expensive and time consuming (RCs and SF6) and subject animals to artificial environments.
The positioning of the subject was the most time consuming part of the process.
