However, computing additive and dominance relationships for all possible pairs of individuals is very time consuming in populations of more than 200 000 animals.
This approach has numerous advantages over the Bayesian method and it does not require time consuming analyses of population structure, as calculations are performed relatively fast [ 64].
Traps are effective for controlling small numbers of mice but are ineffective and time consuming with larger populations.
Most methods used in cell tracking are time consuming and inaccurate for large population density or closely interacting cells.
Moreover, the technique for SFP analysis is costly and time consuming if a large segregating population is genotyped.
Further, interviewees of the implementation team described that the need for local professionals and organizations to get ready to work together first, and the obligated but time-consuming population-based screening had slowed down the implementation of the ZWIP.
These techniques are more time consuming and expensive than using the population based utility weights.
The recruitment campaign was successful in reaching the target population, but was time consuming.
Serial dilution provides a simple, low-cost method for isolating individual cells from abundant cell populations but is time consuming and requires expertise [7].
Wherry is also cautious, pointing out that, aside from the reproducibility issue, it will also be expensive and time consuming to create and house mouse populations with the desired immune profiles.
However, genotyping of large populations using this technique is still expensive and time consuming.
