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The Cartesian grid based triangular elements are employed to avoid the time consuming mesh generation procedure.
Compared with the traditional Sanger method, which is expensive and time consuming, next-generation sequencing (NGS) technologies or massively parallel sequencing technologies (e. g. Illumina/Solexa-based RNA-Seq technology) are much simpler and more cost-effective [ 17].
Thus, the problem of expensive and time-consuming generation of time-varying mesh sequences is addressed.
Traditional mammalian expression systems rely on the time-consuming generation of stable cell lines; this is difficult to accommodate within a modern structural biology pipeline.
Since the completion of the Arabidopsis genome, functional genomics approaches have enabled significant progress on the elucidation of glucosinolate biosynthesis, although in planta validation of candidate gene function often is hampered by time-consuming generation of knockout and overexpression lines in Arabidopsis.
Moreover, the time-consuming generation of stable transgenic lines might limit the use of this bioassay for high-throughput applications.
62 This strategy should ensure physiological expression levels of a biosensor and avoid the time-consuming generation of knockout (or knockdown) cell lines.
All of these issues then need to be evaluated and weighed against the laborious and time-consuming generation of stable cell lines which could eventually lead to improved process yields.
An important limitation of this approach is the time consuming and expensive generation of mice with several mutations.
Kendall et al argue that the time consuming nature of data generation and concerns about small sample size should not deter researchers from using multiperspective qualitative interviews.
Architectural reconstruction and modeling tasks have been handled as either time consuming manual processes or procedural generation with difficult control and artistic influence.
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