He viewed sculpture, he said, as a matter of "time-consuming difficulty," with which stone obliged.
This may be partly ascribed to the time-consuming difficulty of producing cameo glass: it took John Northwood three years to produce the first glass replica of the Portland Vase in 1876.
The low number of contacts of active TB cases with boosting identified over three years (6%), the cost and the time consuming beyond the difficulty in distinguishing boosting from TST conversion in the second TST suggests that the strategy of two-step TST specifically among contacts of active pulmonary TB cases for identify boosting subjects may not be worthwhile.
With newer scanners, coverage of the whole skeleton with MRI by use of whole-body coil arrays or moving table arrangements is possible but it is time consuming, and the difficulty with MR interpretation of certain areas, such as ribs, does not make such intensive imaging worthwhile.
However, there is no doubt that administration of programs such as SQL*LIMS™ are time consuming due to difficulties in template and interface programming.
The drawbacks of the step method are related to its programme complexity, the fact that it is time consuming and the difficulties in data treatment/interpretation [20].
First, the drawing of huge atomic structures is time consuming due to the difficulty of positioning harmoniously the atoms and their bonds.
Sequential stent and nasocystic catheter insertion may be time consuming because of the difficulty in recannulating the pseudocyst after the initial stent placement.
Such measurements were time consuming, due to the difficulty of separating individual juvenile thalli at such high densities, therefore we limited them to recruits on large boulders, which we hypothesized had the greatest chance of survival.
The development of FBA models can be time consuming and tedious because of the difficulty in assembling completely accurate descriptions of these sets, and in identifying errors in the composition of these sets.
Although these transgenic mouse strains mirror very closely gastric adenocarcinoma development in humans, experimentation with these mice is relatively time consuming and expensive due to the difficulties to determine tumor growth and the requirement of breeding transgenic mice.
