The model predicts that the hrp regulon is a biologically stable two-state system, with each of the stable states being strongly attractive, a feature indicative of selection for a tightly regulated and responsive system.
Here, we report the development of a tightly regulated tetracycline-responsive human U6 promoter for shRNA expression.
But the Model S, even at 4700-some pounds and the capability to seat five adults plus two children, felt totally different — it felt as responsive and tightly controlled as a manual transmission car nearly half its size and weight.
One particularly striking example of the integration of aptamer evolution with chemical modifications, utilised combinatorial chemistry techniques during the selection process to generate a new moiety which tightly binds the transactivational responsive (TAR) element of HIV-1 [5].
Once the JA signal reaches its threshold level, genes encoding JA biosynthetic enzymes, which are tightly regulated by JA-responsive transcription factors (TFs), are up- or down-regulated.
In order to activate the killer gene expression only at expected condition, usually a specific environment, the promoter that controls bacteria programmed cell death needs to be easily controllable, tightly regulated and environment-responsive.
nBAF complexes bind tightly to the Ca(2+ -responsive dendritic regulator CREST and directly regulate genes essential for dendritic outgrowth.
The expression of At2-MMP is tightly controlled in a tissue-responsive way during stress conditions.
Namely that key developmental genes like members of the HOX family tend to be tightly expressed [ 33] while environmentally-responsive genes such as yeast detoxification genes change markedly in a variety of stressful conditions [ 34].
Ahir Shah is at Laughing Horse at the Counting House, Edinburgh, 6-30 August Juliet Meyers: The punters here, who are always packed in tightly, are comedy-savvy, locally sourced and responsive.
