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They're in a tightly regulated environment.
Which was their great existential error of judgement, as they sought to eschew editorial responsibility while simultaneously working to dominate and crush traditional media outlets which do operate within a more tightly regulated environment (and, at least in some instances, have a civic mission to truthfully inform).
Thus, the heterogeneity amongst experimental mouse tumours would be expected to be somewhat less, due to their homogenous genetic background and tightly regulated environment and dietary intake.
Several hours before the start of the assay, the salt solution was placed in the container to provide a constant relative humidity (water potential), providing a tightly regulated environment for leaf water loss.
The NP cellular and extracellular matrix (ECM) is a tightly regulated environment where homeostasis is maintained by the matrix metalloproteinases (MMPs), the ADAMTS family of enzymes (A disintegrin and metalloproteinase with thrombospondin motifs), tissue inhibitors of metalloproteinases (TIMPS), and regulation of inorganic pyrophosphate (PPi) transport by ANK [ 11, 12].
Similar(55)
Virulence gene expression of Y. pestis is tightly regulated by environment signals, including temperature, nutrients, growth phase, osmolarity and pH.
In order to activate the killer gene expression only at expected condition, usually a specific environment, the promoter that controls bacteria programmed cell death needs to be easily controllable, tightly regulated and environment-responsive.
A Defra spokesperson said: "Pesticide use across Europe is tightly regulated to protect the environment and public health – [pesticides] are a safe, effective and economical means of managing crops.
This global increase in primary inflammatory cytokine signalling suggests a tightly regulated cytokine-cytokine receptor environment within the FGT.
Expression of virulence genes from the pathogen is tightly regulated, depending on the respective environment, and the SsrB response regulator of the SsrA/SsrB two-component system represents one of the major virulence modulators that controls about 4% of the S. enterica genome including ssrB itself and genes in various SPIs [ 23].
Ergosterol concentration is a major determinant of membrane fluidity, which is tightly regulated according to the cellular environment (Brown and Goldstein, 2009; Burg and Espenshade, 2011).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com