Sentence examples for tightly involve from inspiring English sources

Bone tissue has a strong intrinsic regenerative capacity, thanks to a delicate and complex interplay of cellular and molecular processes, which tightly involve the immune system.

Apart from its involvement in invasion and metastasis of cancer, HPA is tightly involved in angiogenesis, primarily by means of releasing heparin-binding angiogenic factors sequestered by HS in BM and ECM, such as basic fibroblast growth factor, vascular endothelial growth factor, keratinocyte growth factor and hepatocyte growth factor [ 29, 30].

Moreover, the missing data imputation was not tightly involved in the cluster forming process.

Native defects in α-MgAgSb are frequently reported experimentally and are tightly involved in the thermoelectric properties of α-MgAgSb.

It is likely that large-conductance Ca2 +-activated K+ (BKCa) channels channelopathy tightly involved in vascular malfunctions and arterial hypertension development.

Clinicians therefore are tightly involved in the delivery of CBRC, whether as service providers or service facilitators, and have a unique ethical responsibility to ensure that appropriate standards of care are provided to all those receiving treatment, be they patients or third-party providers.

Thus, LRP1 is tightly involved in the control of growth regulating signaling processes that involve TGFβ, PDGF, and their receptors.

This event is expected to be related with Rho and Rac small G-protein activities, which are tightly involved in the initiation and expansion of AJ (59).

Because CDT2 is tightly involved in the initiation of DNA replication and cell cycle regulation, and probably deregulated CDT2 expression could promote carcinogenesis accompanying genomic instability, these considerations strongly support the possibility that CDT2 could be a plausible transcriptional target of E2Fs.

This further support the model we proposed several years ago where the assembly of the prion Ure2p is driven by the establishment of intermolecular interactions between the N- and C-terminal domains of two consecutive Ure2p dimers and where the functional C-terminal domain of the protein is tightly involved in the fibrillar scaffold.

Because Boucher et al. reported that LRP1 is tightly involved in the pathogenesis of atherosclerosis by regulating signaling of TGFβ and PDGF, and their receptors [27], [28], knockdown analysis using LRP1 siRNAs was perfomed to examine the role of LRP1 in the regulatory effect of PDGF-induced Col4 expression and PDGF-activated TGFβ signaling pathway in MCs.