Dimerization has been used by this flavoenzyme in evolution to achieve maximal activity, a tighter interaction between the protein moiety and the coenzyme, and higher thermal stability.
As a result, a tighter interaction between PHY and MAC layers is achieved [14 16].
It is expected that the elimination of the buffer resulted in a tighter interaction between the different components.
Mutation to 123L and 146F, which are similarly hydrophobic but much larger, are predicted to result in a much tighter interaction between these residues.
The observed increase in binding affinity is likely due to removal of potential alternative competing structures, thus allowing a tighter interaction between the protein and the RNA.
The relative ω values for Crm1 suggest a tighter interaction between the human Crm1 monomers, but the absolute value of ω > 1 for murine Crm1 still suggests some interaction between monomers.
Similarly, binding of either ATP, ATPγS or ADP to ClpX led to the same degree of FRET changes in an experimental setup monitoring the formation of "L" subunits, which show tighter interaction between the large and small subunit of the AAA domain [Stinson, BM, et al, Cell, 2013].
The stable device/neuronal electrical coupling at the interface requires tight interactions between the electrode surface and the cell membrane.
Designing cyber-physical systems (CPS) is challenging due to the tight interactions between software, network/platform, and physical components.
Yeast 3′,5′-bisphosphate nucleotidase, also known as HAL2, hydrolyzes 3′-phosphoadenosine 5′-phosphate (PAP) with submicromolar Km, which indicated the tight interactions between HAL2 and PAP.
