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While both the DEL and EVL showed highly coordinated migration toward posterior sites in control embryos (Fig. 7, left column; Supplementary Movie S1), cells of the DEL in cfl1-morphants did not form tight attachments and showed a clear gap with EVL cells (Fig. 7, right column; Supplementary Movie S2).
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These sophisticated constructs were covalently functionalised with the gadolinium (Gd) chelating agent, diethylene triamine pentaacetic acid (DTPA), enabling tight attachment of Gd atoms onto the nanotube surface.
To examine the effects of equipment attachment types, the mass bodies representing the equipment are attached with a spring and damper, with low and high stiffness values indicating loose and tight attachment respectively.
SEM observations of the cell scaffold construct confirmed the tight attachment of chondrocytes to CG-PLLA NF and in-growth of cells into the interior of the membrane with proper maintenance of cell morphology.
Synapses, the junctions between nerve cells through which they communicate, are formed by the coordinated assembly and tight attachment of pre- and postsynaptic specializations.
Interestingly, only the tight attachment of hyphae to the root surface displayed the possibility of infection, suggesting that substantial interaction between the host and hyphae was necessary for triggering hyphae penetration.
A tight attachment occurs as soon as 1 hr after the co-incubation of the bacteria and fungus.
Thus, cells with normal epithelial morphology exhibit retention of cell surface HSPGs and tight attachment to the extracellular matrix.
This tight attachment is mediated by integrins, which are activated by chemokine signalling via the so-called 'inside-out' signalling.
Recognition of DAF, CEA, and CEACAM6, but not of CEACAM1, is accompanied by the induction of microvilli extensions at the cell surface, promoting the tight attachment of bacteria.
These can possibly evolve into retinal detachment, since the detached vitreous often displays tight attachment points with the retina, where concentrated mechanical stimuli occur [ 1].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com