Sentence examples for tight affinity with from inspiring English sources

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In this respect, the property whereby macroH2A1.1 binds with very tight affinity with OAADPR produced by SIRT1 is intriguing, considering that the activation of these enzymes is considered protective against NAFLD favouring a overall healthy aging [ 38], and is under scrutiny for drug design [ 39, 40].

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You could sense the players' close affinity with each work.

Until then, humans had a close affinity with nature.

The AHNAK peptide adopts a coil conformation that arches across the heterotetramer contacting both annexin A2 and S100A10 protomers with tight affinity (∼30 nM) and establishing a structural rationale whereby both S100A10 and annexin proteins are needed in AHNAK recruitment.

Diabetes susceptibility alleles are predicted to bind autoantigens strongly with tight affinity, prolonged association and altered cytokine expression profile.

The lipophilic hydrophobic properties of vitamin D, coupled with its tight affinity to vitamin D binding protein, have made it challenging to measure.

This approach performs a better search when there is a tight affinity.

This is also in agreement with the tighter affinity of Josephin with the highly homologous Ubl of hHR23B (12 µM) as compared with the Kd of ∼50 µM for the complex with monoUb [17].

As expected, the wild-type L7Ae/K-turn pair, which caused strong translational repression in our previous report, bound with the tightest affinity, and the measured KD of 1.6 nM was consistent with previously published measurements.

This suggests, the researchers contend in their paper, that "the La Braña individuals had tight cultural affinities with those distant regions".

The F220H complex formed with ∼5 fold tighter affinity than F53H (KD, 70±10 nM) revealing that the extended structure may present extra Hfq binding elements or a more favorable Hfq-binding motif (Figure S3).

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