In 2001, Novartis offered WHO an "at-cost" tiered price for developing countries of $2.40 per adult treatment course for artemether-lumefantrine (AL; Coartem®) [ 29].
These premium tiers cost $5 per employee per year for business users, or $45 per teacher per year with support for an unlimited number of students.
But for the more elaborate ones, the company plans to use a subscription model, possibly with two tiers costing $4.95 and $9.95 a month respectively.
From December a Foxtel Play subscription will be available from $10 a month; after that each tier costs $10 (kids), $15 (drama) or $25 (sport).
Mobile Roadie's mobile web tier costs $9 a month or $99 a year, with a key selling point being the fact that the resulting sites will play nice with Windows Phone, BlackBerry and Symbian smartphones as well as iOS and Android.
The Business Pro tier costs €79/month, offering access to up to 25 people, while the Business Enterprise tier costs €1,499/month, offering access to up to 1,000 employees.
Symphony's pricing is freemium, with its paid tiers costing $15/user/month.
Basic services cost $9.99 per month, and a higher tier costs $19.99 for high-definition audio quality.
The normal tier costs €12 per month, and there's a lower offering for €10 per month limited to laptops, tablets and phones.
Some have suggested that a first-tier cost-effective WES might be a powerful way to dissect the genetic basis of diseases and to facilitate the accurate diagnosis of individuals with 'Mendelian disorders' [ 26, 27].
If permission were granted by a local government, frequent remote metering would also enable utilities to tier energy costs, charging customers different amounts depending on the time of day, as electric utilities often do with their business accounts.
