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The high expression of the midnight blue module appeared largely restricted to the nucleus accumbens, while the purple module displayed a very distinctive dorsal tier pattern of expression within the caudate putamen.
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We present a recently introduced three tier pattern-based histopathologic system to stratify endocervical adenocarcinoma (EAC) that better correlates with lymph node (LN) metastases than FIGO staging alone, and has the advantage of safely predicting node-negative disease in a large proportion of EAC patients.
The second tier patterns are obtained by calling the Next_Tier from the first tier solutions.
The same two-tier pattern, with its attendant tensions, was repeated in 1965 when the LCC was replaced by the Greater London Council.
Changing the two-tier rescue pattern so each EMS subgroup cooperated with two specific, preassigned network hospitals lowered the probability of patients having to wait for rescue dispatch to under 1%.
In Leicestershire, Leicester and Rutland would become unitary authorities, with the rest of the county remaining two-tier – a pattern followed also in County Durham (Darlington), Devon (Plymouth and Torbay), East Sussex (Brighton & Hove), Essex (Southend-on-Sea), Nottinghamshire (Nottingham), Staffordshire (Stoke-on-Trent) and Wiltshire (Thamesdown).
LABOR Day may have been upon them, but in the summer of 1990 fashion die-hards clung to the faded remnants of the season, whisking around town in breeze-catching, ankle-length skirts that were tiered, whimsically patterned or pleated in the manner of a Grecian nymph.
Most spiralian embryos exhibit tier-specific patterns of cell division at early stages; the significance of this mitotic asynchrony is unknown, but presumably reflects differential inheritance of factors regulating cell division.
Moreover, the content of Proportional Reasoning shows the opposite pattern: tier 1 items are actually harder on average (average difficulty estimate of 0.57), whereas the tier 2 items are relatively easier on average (average difficulty estimate of −0.40).
This approach is taken because we do not yet know if the cognitive skills associated with the tiers exhibit a consistent pattern of difficulty across all content (for example, that tier 1 is always easier than tier 2), or whether the tiers vary in difficulty according to content.
Findings for CTSR do not show a consistent pattern by tier or by content sub-topic.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com