Significant efforts have been made to exploit NIS for developing radioiodine-based diagnostic and therapeutic procedures in non-thyroid malignant diseases has been reviewed.
Coronary patients and control subjects with history of renal, liver, thyroid or malignant disease, and corticosteroid use were not included.
No association was found between endometrial adenocarcinoma and obesity, diabetes mellitus, thyroid disease or extragenital malignant disease.
Well-differentiated thyroid carcinoma is considered an indolent malignant disease.
A total of 5,611 surgical specimens resected for benign or malignant disease of the thyroid gland concerning 1,114 males and 4,497 females (M/F-ratio: 1 4) were examined.
In this study, gene expression data were used to build BNNs and to perform discriminant analyses in order to discriminate between benign and malignant disease and predict the probability of thyroid cancer for individual patients.
Summing up the odds ratios for "all other malignant disease" (except for pancreatic carcinoma and thyroid cancer) resulted in significantly reduced odds ratios regardless of whether insulin-treated patients were used as control subjects.
When taking into consideration all malignant disease categories together (including pancreatic carcinoma and thyroid cancer), the analysis demonstrated not an overall increase in the odds ratio for "all malignant disease" but, rather, a trend toward a reduction, especially with sitagliptin treatment (P = 0.068; not significant [details not shown]).
Cowden syndrome is characterized by multiple hamartomas in various tissues, including the skin, brain, breast, thyroid, mucous membrane, and gastrointestinal tract, and is reported to increase the risk of malignant disease.
Our research is focused on benign and malignant diseases of the thyroid, parathyroid, pancreas, and adrenal glands.
The objectives of the present work were two-fold: 1 – to study, and compare, the relative expression of PPAR γ in the normal gland and in benign and malignant diseases of the thyroid; and 2 – to correlate PPAR γ immunostaining with clinical and pathological characteristics of patients with thyroid carcinomas of follicular origin.
