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Thus, we generated a series of 5'-deletion constructs to test the general responsiveness of the promoter to AICAR and also to identify the regulatory regions responsible for regulating PGC-1α transcription.
Thus, we generated and added another operator to this algorithm.
Thus, we generated TARGOMICs, optimized for detecting chromosome alterations by combining allelic ratios and read counts generated by targeted NGS.
Thus, we generated several subdomains from this spatial subdivision and from the different variables and time steps.
Thus, we generated four nematode strains; one strain of each species solely exposed to R sheep and one strain of each species solely exposed to S sheep.
Thus, we generated the first tricistronic podocyte mouse model combining enhanced Cre recombinase efficiency and fluorescent labeling in podocytes without the need for additional matings with conventional reporter mouse lines.
Thus, we generated CD19-specific CARs with IgG4-Fc spacers that had either been mutated at two sites (L235E; N297Q) within the CH2 region (CD19R(EQ)) or incorporated a CH2 deletion (CD19Rch2Δ).
Thus, we generated sets of FR values for each IP-protein for which we had a reliable antibody.
Thus we generated a SACOL1828::tet mutant in SH1000, before transducing it with the sigS-lacZ reporter-gene fusion.
Thus, we generated starting models for each structure by randomly perturbing the coordinates for each atom of the deposited PDB structural model.
Thus, we generated triple transgenic mice (SIRT1ΔSTOP; Vil-Cre; APCmin/+) which overexpress SIRT1 specifically in the gut villi (referred to as SIRT1ΔSTOP).
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