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The leaked emails are thus profoundly inconvenient for all of us who are concerned to make the world wake up to an inconvenient truth.
Whether it can be accommodated with the seamless web of current knowledge – and thus profoundly change it – may depend upon whether enough people take it seriously enough to do the calculations and follow through the consequences.
But humans do have such a capacity and are thus profoundly different from even the higher animals, which deal with impressions merely in an unreflective way (2.8).
In this species, mate choice may thus profoundly affect reproductive success throughout an individual's lifetime.
This is particularly true in the setting of microvasculature as it provides endothelial exchange surface area for substrate exchanges and metabolic waste removal and thus profoundly affects cell metabolism, function and health.
Altered expression of critical miRNAs, such as miR-146a and miR-155, thus profoundly contributes to the pathogeneses of rheumatic diseases, where dysregulation of their target proteins leads to unabated inflammatory cytokine production and signaling, and aberrant priming of adaptive immune response.
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The dynamics of the uprising thus changed profoundly, as it could now jeopardize the status of the entire manorial system.
Impairment of oxygen delivery, inflammation, sepsis and other ICU-associated pathologies, all impose cellular stress and thus will affect profoundly mitochondrial physiology.
An increasing fusion of biomaterials technologies and stem cell biology thus promises to profoundly impact stem cell biology and tissue engineering, hopefully moving the field one step closer to the clinic.
Thus, arginine withdrawal profoundly affects tumour cell physiology.
In this thickness regime the electronic transport and, thus the conductivity are profoundly determined by the surface topography and the film density.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com