The phrase 'thus making it difficult' is correct and usable in written English.
You can use it to indicate that something is the cause of an obstacle or difficulty. For example, "The complicated instructions for the project were poorly written, thus making it difficult to understand how to complete it."
A Seagram spokesman argued that such comparisons were not valid because the company's stake in DuPont was illiquid, thus making it difficult for the company to realize its value, regardless of the stock price.
You can keep changing the interface, thus making it difficult for the parasitic product to bite into its host and suck its blood (data, in this case), or you change the licensing terms.
However, MAS is usually designed to meet special need, thus making it difficult to follow a standard.
The literature reviewed was primarily comprised of small open-label trials, thus making it difficult to draw definitive conclusions.
There are a multitude of factors that can affect a currency's value, thus making it difficult to isolate the effect of the DBCFT.
Making matters worse, it is common practice for physician assistants to work back-to-back shifts at different hospitals, thus making it difficult to track their hours.
But the Iranians were told that the United States had found out about the 1994 sale, thus making it difficult to hold any further sales negotiations.
Operators of online games and virtual worlds are often apathetic towards sharing internal data, thus making it difficult to do research in the field.
Particularly if those nations have strong policies on financial privacy, thus making it difficult for uncompetitive high-tax nations to track and tax flight capital.
This trend contributes to further crowding the market for entry-level homes and tightening inventory even more, thus making it difficult for new homeowners to enter the market.
The pressure mine reacts only to a pressure change produced by a ship larger than a minesweeper, thus making it difficult to clear.
