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The highly conserved N-terminal domain (NT) folds into a soluble ∼130 residue 5-helix bundle with a dipolar charge distribution28,29 and forms antiparallel dimers at a pH below 6.5 (refs 30, 31, 32, 33, 34, 35), thus interconnecting spidroins in the spinning duct (Fig. 1a).
SigB of L. monocytogenes is also acting on the transcription of prfA and hence of PrfA-dependent genes, thus interconnecting stress response and virulence gene expression [31], [32], [33], [34], [35].
Interestingly the expression of GLUT1 also appears to be regulated by mTOR, 42 thus, interconnecting glucose uptake with mTOR signaling (see below).
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The two 'baskets' of challenges, definition of biobanks in different languages and the legal challenges, are thus interconnected in work to develop a Europe-wide information model.
This figure suggests that the network topology exhibits a core-periphery dichotomy [ 36, 37] - about half of the nodes in this network interact frequently and are thus interconnected densely to form an inner 36-core, while others communicate with fewer nodes and scatter in different outer core layers to form the periphery of the network.
Theories of truth and meaning are thus inherently interconnected.
Moreover, WDNs are part of a city's infrastructure system and thus are interconnected to all essential lifeline networks.
Thus, fully interconnected (connectivity: ~ 100%) aligned pores with uniform size were generated in the PCL porous scaffold after PEO extraction.
Further analysis using ClueGO [ 15] demonstrated that many of the enriched GO terms share core response genes in common, and are thus highly interconnected (Fig. 2b).> M. tuberculosis (MTB) infection of macrophages induces an IFN response, and the transcriptional signature of THP-1 cells exposed to different MTB strains has been described [ 16].
Thus, entry points and interconnecting links in major stress-related signalling cascades involve Ca2+ sensors and proteins regulated by Ca2+-concentration gradients between apoplast and cytoplasm [ 28].
The presented fibres allow the processing of a very reproducible intra-architectural scaffold geometry which is fully interconnected, thus providing a high surface area for cell attachment and tissue in-growth.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com