Some of them, like AFM, FRET and BREF, can only be applied on the small scale protein-protein interaction detection, while others, such as Yeast Two Hybrid, Affinity Purification and Protein Arrays, are suitable for high throughput purpose.
We also developed protocols for the high-throughput purpose that use specially designed substrates to hold a large number of resins (as many as 10,000), which avoids cross-contamination among components.
In addition, it is not suitable for high-throughput purpose.
The sequence assemblies were used to identify a set of SNPs suited for high throughput genotyping purposes, and to screen for EST-SSRs.
Large numbers of SNPs amendable for high throughput genotyping purposes were generated for each genotype providing a very rich resource for fast development of markers in lily and tulip.
One task of the European Lead Factory Project (ELF) is to synthesize a new combinatorial library of 200,000 compounds for high-throughput screening purposes [2].
Some chemical structures in PubChem have a great deal of biological annotation and literature associated, while many others (e.g., synthesized for high-throughput screening purposes) have little to nothing known about them other than the chemical structure.
This makes SNP the preferred markers for different high-throughput genotyping purposes.
They have been also screened for SSR motifs and used to identify a large SNPs collection suited for high-throughput mapping purposes.
The primary screening of a kinase inhibitor (KI) library comprised of 244 KIs was purchased from EMD Chemicals, and diluted with DMSO to 2 mM concentrations for high-throughput screening purposes.
The specific probe hybridization pattern obtained from each virus makes this approach a powerful tool for high throughput plant certification purposes and also for virus discovery if the new viral genomic sequences have partial similarity with the microarray probes.
