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The capture process employed in monoclonal antibody downstream purification is not only the most critically impacted process by increased antibody titer resulting from optimized mammalian cell culture expression systems, but also the most important purification step in determining overall process throughput, product quality, and economics.
All facilitate greater efficiencies such as rapid throughput, product protection, lower cost and consumer convenience.
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This method of protein immobilization could be utilized for preparation of high throughput products requiring structurally ordered molecular interfaces, in addition to many other applications.
We establish an information requirements workflow for streamlining information throughput during product realization.
A new in-line reciprocating PVD prototype machine is described that enables a significant increase in throughput and product flexibility over conventional PVD machines.
The potential to produce succinate aerobically in Escherichia coli would offer great advantages over anaerobic fermentation in terms of faster biomass generation, carbon throughput, and product formation.
Ultrafiltration (UF), a membrane-based separation process which combines high throughput of product with ease of scale-up is widely used for protein desalting and concentration.
Both fast positioning and eliminating relative vibration between automatic optical inspection devices and the associated workpieces are critical for enhancing the throughput of product inspection.
There are, though, several competing variants of the dual bipolar process currently employed, with each variant imposing its own set of criteria in terms of cost, process stability, throughput and product performance.
The control architecture aims to achieve independent control of circuit throughput and product quality, and consists of a non-linear model predictive controller for grinding mill circuit control, and a dynamic inversion controller to control the fast sump dynamics.
Increased understanding from the models can lead to improvements in equipment design and operation, potentially leading to large increases in equipment and process efficiency, throughput and/or product quality.
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