This strategy constitutes a general approach to balance the increasing data throughput of the instruments for the preparation of samples for large scale sequencing projects.
In addition, early calorimetric studies on biopsies and tumors were hindered by the lack of throughput of the instruments available in 1970s [ 22– 22].
WGS studies are likely to become more common in the future given that the throughput of the MPS instruments continue to increase, thereby driving down the cost per base of sequencing.
While the first ChIP-seq experiments were limited by the sequencing capacity, the high throughputs of the current instruments allow many ChIP samples to be multiplexed and sequenced simultaneously in a single run.
The particle throughput measured by the instrument was calculated as the quotient of the number of bursts detected throughout the experiment and its duration.
Compliance of the predicted passband throughput model to the spectral positioning requirements of the instrument is also demonstrated.
In these studies, DAE analysis was limited by the single-capillary throughput of the HRM device used, the HR-1™ instrument, and allelic imbalance was quantified manually.
The throughput of the described protocol is currently only limited by the instrument used and a larger liquid handling robot equipped with a 96-tip head could increase the throughput per run to 96 samples or more.
One of the goals of the current work was to increase the throughput of the chemical screening assay by utilizing a commercial instrument to distribute a precise number of infected worms in each microtiter well.
