Sentence examples for through which hypoxic from inspiring English sources
The mechanisms through which hypoxic adaptation occur are poorly understood.
Understanding the mechanisms by which hypoxic tumours can overcome cell death signals and adapt through metabolic changes is critical for our understanding of tumour progression and development of effective therapeutics in CRC patients with adverse prognostic profiles.
The exact mechanism by which hypoxic interneurons maintain higher levels of GSH than hypoxic pyramidal neurons remains unclear.
These data collectively suggested that the genetic manipulation of ERBB4 induced beneficial secretome in conditioned medium, through which cardiomyocytes were protected from hypoxic stress.
We identified the stabilization of HIF-1α protein as a mechanism through which bcl-2 induces the activation of HIF-1 in hypoxic tumour cells involving the β isoform of molecular chaperone HSP90.
Hypoxic regulation of erythropoiesis provided the paradigm through which HIF was discovered and initially investigated.
Our study demonstrates a novel mechanism through which glycolytic pyruvate confers resistance to RIP-dependent necroptosis in hypoxic colorectal carcinoma via mitochondrial superoxide scavenging.
However, the mechanisms through which adventitious roots contribute to flooding tolerance of the tree and those that enable the roots to survive hypoxic conditions remain unclear.
In this context, our present data add a further mechanism through which the tumor microenvironment may promote angiogenesis, as the HIF-1α/GPER signaling was shown to mediate the up-regulation of VEGF expression in CAFs cultured in hypoxic conditions.
The pro-angiogenic effect of TG2 has also been shown through its binding to endostatin in a cation-dependent manner, which under hypoxic conditions leads to stimulation of angiogenesis.
Under these hypoxic conditions, glucose consumption and lactate production rates were similar to aerobic rates until about 12 h after which the hypoxic rates increased.
