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Consequently, the elevated NF- κB activity in PC3 cells may define a multifaceted resistance that functionally antagonises Hsp90-directed therapeutic agents, initially through a promotion of compensatory survival signaling, and then through underpinning the increased expression of Hsp90 in these cells.
So bad was the "excavation, foundation drilling, concreting, underpinning (you want to try to live through underpinning), not to mention shuttering, grinding, drilling and so on," he said, that even earplugs "meant for shotgun enthusiasts" could not drown out the noise.
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Connections between Long and his alter-ego Setepenra were revealed through registration logs underpinning a series of websites.
As in the previous books, Robinson's interest in Calvinism – she described John Calvin recently as a humanist, "terrifically admiring of what the human mind does" – runs through the narrative, underpinning and illuminating the characters' moral dilemmas and choices.
This was achieved through negotiations underpinned by collective information on the services councils commissioned and the needsspecific schools could meet.
"[Levies] have been introduced in other developed markets as a more direct way of ensuring successful PSB outcomes than any retransmission fee regime through negotiation underpinned by a new and potentially complicated regulatory system," said Ofcom.
"The impact of the sovereign debt woes in Europe and the United States and the associated turbulence in stock markets over the summer have not yet fully fed through into the indicators underpinning the projections," the report said.
The paper provides an overview on research activities and technology development through a fundamental research underpinning the Australia/Japan Oxyfuel Feasibility Project.
A final aspect of underpinning the vision through policy is the need for an adaptive policy environment [52].
A vision, known as Iskandar Malaysia, has been facilitated through a Comprehensive Development Plan underpinning strategies to boost the physical and economic development of the Johor Bahru metropolitan area.
It develops a partial analysis on the demand side of transport, clearly isolating its outcomes from potential influence from the supply side; It attempts to go beyond existing analyses by underpinning the analysis through the consideration of a wide range of transversal factors of change to transport demand.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com