In E. coli, the anaerobic stimulon is intimately associated with global regulation through the leucine responsive regulatory protein, Lrp.
It is reported that several extracellular stimuli including butyrate (Nakano et al, 1997), transforming growth factor-β (Datto et al, 1995), phorbol esters (Biggs et al, 1996), okadaic acid (Biggs et al, 1996) and retinoic acid (Liu et al, 1996) activate the transcription of p21 waf1 gene through the Sp1 responsive elements.
Several detoxifying and antioxidant genes, including glutathione- S-transferases (GSTs), heme oxygenase-1 (HMOX1), and thioredoxin (TXN), are regulated by NRF2 through the antioxidant responsive element (ARE) in the respective promoter regions of these genes (McMahon et al. 2001; Wakabayashi et al. 2004).
An alternative approach could be to screen mutants defective in oxalate secretion, followed by cloning of the responsive genes through map-based cloning techniques, to isolate genes encoding oxalate transporters.
"The Responsive Eye: A Brian De Palma Retrospective," through May 27.
Thus, in vitro situation, Hes7 can inhibit the expression of Sprouty4 through the Hes7-responsive elements in the Sprouty4 promoter.
Tax enhances productive virus replication by driving viral gene transcription through the cAMP-responsive element located in the long terminal repeat of the viral genome [3], [4].
A well-known mechanism is through the metal-responsive transcription factor 1 (Mtf1), a recognised zinc-sensory transcriptional activator.
D. melanogaster CG10505 is regulated by heavy metals through the metal-responsive transcription factor 1 (MTF-1) and contributes to metal homeostasis [ 80].
