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The inhibitor enhances the response of tumor cells to radiation through the prolongation of γ-H2AX foci.

This indicates that a delayed intervention in a clinical situation leading to a secondary haematoma in the fractured region may delay the healing process through the prolongation of the pro-inflammatory phase.

These results indicate that MDA attenuates the capacity of encoding sequential spikes through the prolongation of absolute refractory periods (Fig. 4).

Hypokalaemia is known to predispose to cardiac arrhythmias at the clinical (Berthet et al. 1999) and experimental (Killeen et al. 2007a) levels through the prolongation of APD and the subsequent development of EADs, which superimpose upon an arrhythmogenic substrate of altered transmural gradients of repolarization (Killeen et al. 2007b).

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MGlu5 mediates the prolongation of synaptic plasticity through a variety of mechanisms.

A study of the 2009 H1N1 epidemic in Mexico, for example, concluded that the prolongation of the epidemic through a second wave was induced by the private response to social distancing measures implemented by the health authorities (Herrera-Valdez et al. 2011).

Taking all this information into consideration, the discovery of novel, reliable molecular biomarkers for HNSCC may contribute to the prolongation of patients' survival through early diagnosis, reliable prognosis and/or effective treatment response monitoring, while it may also illuminate the molecular background of this cancer type [ 41].

Tumors with missense mutations displayed positive nuclear immunoreactivity of p53 for the effect of mutation on the prolongation of p53 half-life through increased protein stability [ 35].

Here we show that the evolution of bone loss in Antarctic notothenioids can be explained in part by the prolongation of the early chondrogenic developmental pathway through extended periods of larval development.

"The prolongation of my case has been an obstacle to getting better".

This is what must be considered in the prolongation of futile treatment.

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