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These unusual antibodies can be elicited to recognize defined antigens through the knob domain.
Adenovirus type 5 (Ad5) binds to its receptor CAR through the knob of its fiber, and internalizes into the host cell with the recognition of Arg-Gly-Asp (RGD) motif in the penton base by integrins.
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This arrangement of amino acids forms a hydrophobic seam and results in the formation of a coiled coil through the knobs-into-holes arrangement of side chain packing, forming the hallmark or structural signature of a coiled coil.
It also was on Redding's cellphone, which had been used to make a 911 call that did not go through, and the knob of a stove that was left on, filling the home with gas.
The band is designed to offer a snug and secure fit, threading one end through a hole in the other and pushing the knob through a center hole.
A burglar enters a residence by breaking a window in the front door, reaching through the door and turning the knob.
"I opened the door for a lot of people, and they just ran through and left me holding the knob," he told The New York Times in 2003.
Some leagues require players to tape the butt-end so that the knob cannot fit through your face cage.
IV Turn the knob, open the door, step through the frame.
Turn the knob, pull open the door, step through the frame.
Once you have AM, you push the knob and sadly use yet another switch to scan through stations.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com