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Validity evidence for the CAPL theoretical model and assessment protocols as an whole, was first generated through a Delphi process [ 19] and then further supported through the confirmatory factor analysis reported in this manuscript.
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Break out session 4 captured the current practice in the application of M&S in the confirmatory stage of development through case studies that have either been submitted to European regulators or would be considered to be of high impact within the new EMA regulatory framework.
GZ carried out the confirmatory analysis of microarray experiments through quantitative real time-PCR and various technical assistance and advice.
So he sent off the confirmatory test.
Phase 3: conducting the confirmatory experiment.
The confirmatory model was performed on the entire sample (confirmatory dataset) currently available (n = 40).
Results of the confirmatory trial, which enrolled more than 80,000 subjects in the Netherlands, are expected in 2013.
As the confirmatory bioassays most likely have a lower false positive rate and suggest a more accurate activity measurement, both target and target cluster-based analysis were carried out based on test results reported through confirmatory bioassays, in addition to the analysis using all of the available screen results for providing general background information.
RMRN was responsible for the confirmatory diagnostics.
The confirmatory tests utilized are described below.
HJA performed the confirmatory factor analysis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com