Sentence examples for through slippage from inspiring English sources

Homopolymeric tracts are hypermutable: they are highly prone to gaining or losing repeats through slippage, thereby producing indels.

To change the color, the pitch needs to adjust to the field, either through slippage at the bounding plates or through nucleation and propagation of dislocations; some of these defect lines are seen in Figure 2b e.

The constant formation of DNA microsatellites through slippage by the replication machinery, and the action of viruses and transposons, also complicate the word landscape, especially in regions with lower selective constraints (such as introns, UTRs and intergenic regions) [ 6, 7].

Variation in the length of microsatellite motifs in non-coding sequences of genes (i.e. promoters, UTRs and introns) may affect the process of transcription and translation through slippage, gene silencing and pre-mRNA splicing as has been observed for many diseases in humans, including cancers and neuronal disorders [ 3- 9].

Breaking and reforming of the xyloglucan chains, that inter-connect cellulose microfibrils, by wall glucanases [ 4] and xyloglucan-endotransglycosylases (XETs) [ 5, 6], and/or disruption of attachment sites between cellulose and xyloglucan by expansins [ 7], may then promote longitudinal growth through slippage of the microfibrils.

Richardson says that the study team has identified a transition zone between the upper crust, where big earthquakes go off on the rare occasions when there is slip, and the deep, soft crust, where the fault grinds along more quietly, through the slippage of nearly continuous little tremors.

However, after in vitro and in vivo passages, such changes were only observed in one of the two genes, implicating another mechanism, and repeat units were possibly deleted through intragenic slippage during replication.

Younger CR1 elements starting with one octomer gain repeats through this slippage mechanism during replication.

Alternatively, mutations could be generated in the terminal octomer through a slippage effect during replication.

Furthermore, we show that progression through mitotic slippage can enhance senescence induced by weak oncogenic signaling.

Second, the ancestral 89-nucleotide long segment does not contain any repetitive element to justify duplication through replication slippage and/or non-homologous recombination.