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Recombination creates conflicting phylogenies among distant loci through reshuffling of DNA sequences among different genomes.
At the cell level, somatic cells can become dedifferentiated and heterogeneous, through reshuffling of the genome and remodelling of the epigenome by reactivation of retrotransposons.
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After purification by immobilized metal ion affinity chromatography, refolding in vitro through disulfide reshuffling, and digestion by endoproteinase Asp-N, mature human relaxin-3 was obtained in high yield and at low cost.
The relevance of recombination in HCV for its long-term evolution and its incidence in different aspects of HCV infection have not been explored yet, but these findings support a potentially significant role for recombination in the evolution of HCV by creating genetic variation through the reshuffling of independently arisen variants.
We found that diversification of the WD-repeat domains occurs through intragenic reshuffling in the repeat arrays.
A mixnet provides anonymity via packet reshuffling through (at least one trusted) "mix".
An alternative way to enhance efficient use of nuclear fuel is investigated through fuel pin reshuffling options within PWR fuel assembly (FA).
The poll numbers went through a major reshuffling right after the second Republican debate, so there's always a chance this could happen again after the next one.
Other members of the CMN group were shown to have evolved through important DNA reshuffling.
The recombination rate calculated in the present study was five orders of magnitude higher than the estimated mutation rate, and recombination should therefore be considered as a key player in genome reshuffling through the occurrence of rearrangements.
Furthermore, analysis of the DNA that directly flanks these two inversions revealed the presence of sequences specifying mobile elements/transposases, which may have acted as mechanistic drivers for this genomic reshuffling through homologous recombination [ 20].
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